货号 | DY086028 |
---|---|
品牌 | abinScience |
样本类型 | Plasma, Serum |
灵敏度 | 0.156 μg/ml |
检测范围 | 0.31-5 μg/mL |
Accession号 | P10636 |
应用 | ELISA |
检测方法 | Colorimetric |
实验类型 | Quantitative |
回收率 | 80-120% |
运输 | 2-8 ℃ |
稳定性和存储 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
规格 | Tilavonemab |
别名 | ABBV-8E12, C2N-8E12, CAS: 2096513-89-0 |
背景 | Tilavonemab (ABBV-8E12) is an antibody recognizing the aggregated, extracellular form of pathological tau and binding to the N-terminus of tau. This drug was developed by C2N Diagnostics and AbbVie and has been validated for its safety in a phase I trial. However, the phase II trial, evaluating the efficacy and safety of tilavonemab in 453 patients with early AD, did not obtain expected results and now tilavonemab is discontinued in AD treatment. In addition, a phase II trial purposed to assess the long-term safety and tolerability of tilavonemab in 364 participants with early AD was finished in September 30, 2021, but its final reports are not available. |
Note | For Research Use Only. |
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