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Anti-Golimumab Neutralizing Antibody ELISA kit (AF879078)

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概述
货号AF879078
品牌abinScience
描述
Anti-Golimumab Neutralizing Antibody ELISA kit (AF879078) is an antibody detecting Golimumab Neutralizing.
样本类型Serum, plasma, and other biological fluid samples
灵敏度9.33 ng/mL
检测范围15.63 - 1,000 ng/mL
种属反应性Human
靶标TNFa/TNF-alpha
Accession号P01375
应用ELISA
检测方法Colorimetric
实验类型Competitive
回收率80-120%
运输2-8 ℃
稳定性和存储The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
背景Golimumab (Simponi®) is a human immunoglobulin G1? monoclonal antibody which is specific for pro-inflammatory cytokine, tumor necrosis factor-a (TNFa). In 2009, it was approved by FDA for the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis in adult patients. Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis, including juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis patients and play an important role in both the pathologic inflammation and the joint destruction that are hallmarks of these diseases. Increased levels of TNF are also found in psoriasis (Ps) plaques. Golimumab binds to both the soluble and transmembrane bioactive forms of human TNF and prevent TNF from binding to its receptors and finally inhibits biological activity of TNF.
NoteFor research use only
图片

  • Standard Curve

    Standard Curve of Anti-Golimumab Neutralizing Antibody ELISA kit

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Golimumab Neutralizing Antibody ELISA kit

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