货号 | DY403028 |
---|---|
品牌 | abinScience |
样本类型 | Plasma, Serum |
灵敏度 | 0.156 μg/ml |
检测范围 | 0.31-5 μg/mL |
Accession号 | P10646 |
应用 | ELISA |
检测方法 | Colorimetric |
实验类型 | Quantitative |
回收率 | 80-120% |
运输 | 2-8 ℃ |
稳定性和存储 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 20% prior to the expiration date under appropriate storage condition. |
规格 | Concizumab |
别名 | Anti-TFPI, NN7415, mab2021, 1312299-39-0 |
背景 | Concizumab (mAb 2021) is a high-affinity, humanized, monoclonal IgG4 antibody (mAb) developed by Novo Nordisk A/S. It was directed against the Kunitz-2 domain of human tissue factor (TF) pathway inhibitor (TFPI), designed to target and selectively block the factor X (FX) a (FXa) binding site of TFPI. As a mAb, concizumab has the advantage of being administered subcutaneously, and exhibits good solubility and stability, allowing administration as a liquid formulation via a ready- and easy-to-use portable pen device. Phase 2 trials of concizumab are ongoing for Haemophilia A and B. On 12 October 2017, orphan designation (EU/3/17/1940) was granted by the European Commission to Novo Nordisk A/S, Denmark, for concizumab for the treatment of haemophilia B. |
Note | For Research Use Only. |
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