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Farletuzumab ELISA Kit (DB825018)

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  • 96T
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概述
货号DB825018
品牌abinScience
描述
Farletuzumab ELISA Kit (DB825018) — Quantitative sandwich ELISA for Farletuzumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
  • ●Sandwich Format — High specificity, reliable quantification.
  • ●High Sensitivity — Optimized for low-abundance target detection.
  • ●Ready-to-Use — Complete kit with pre-coated plates included.
样本类型Plasma, Serum
灵敏度0.156 μg/ml
检测范围0.31-5 μg/mL
Accession号P15328
应用ELISA
检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
稳定性和存储The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
规格

Farletuzumab

别名M3, MORAb-003, MORAb-003-VCP-eribulin, MORAb-202, 896723-44-7
背景

Folate receptor alpha (Farletuzumab) is a ~29 kDa protein. Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

1. Zhao, R. et al. (2009) The Journal of biological chemistry 284, 4267-74. PMID: 19074442
2. Chen, C. et al. (2013) Nature 500, 486-9. PMID: 23851396
3. Wibowo, AS. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 15180-8. PMID: 23934049
4. Lacey, SW. et al. (1989) The Journal of clinical investigation 84, 715-20. PMID: 2527252
5. Orr, RB. et al. (1994) Cancer research 54, 3905-11. PMID: 8033114
6. Rijnboutt, S. et al. (1996) The Journal of cell biology 132, 35-47. PMID: 8567728
NoteFor Research Use Only.
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参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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