| 靶标 | Genome polyprotein, Core protein precursor, Capsid protein C, p23, Mature core protein, p21, Envelope glycoprotein E1, gp32, gp35, Envelope glycoprotein E2, NS1, gp68, gp70, Viroporin p7, Protease NS2, p23, 3.4.22.-, Serine protease/helicase NS3, 3.4.21.98, 3.6.1.15, 3.6.4.13, Hepacivirin, NS3 helicase, NS3 protease, NS3P, Viroporin p70, Non-structural protein 4A, NS4A, p8, Non-structural protein 4B, NS4B, p27, Non-structural protein 5A, NS5A, p56/58, RNA-directed RNA polymerase, 2.7.7.48, NS5B, p68 |
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| 背景 | Genome polyprotein is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication (Probable). Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). |
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