

| 货号 | ZA029023 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Centruroides (Mexican scorpion) | ||||
| 应用 | ELISA, Neutralization, SPR | ||||
| 同种型 | IgG2a | ||||
| 克隆号 | 4B | ||||
| 靶标 | Beta-toxin Cl13, CliNaTxBet37, Beta-toxin Cb3, Centruroides limpidus (Mexican scorpion), Centruroides baergi (Scorpion) (Centruroides nigrovariatus baergi) | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | C0HK69, C0HLR5 | ||||
| RRID | Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (4B) (abinScience Cat# ZA029023, RRID:AB_3729011) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Beta-toxin Cl13 (Cb3) is a ~8 kDa protein. Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. Inhibits sodium channels Nav1.4/SCN4A, Nav1.5/SCN5A and Nav1.6/SCN8A. Also has a weak inhibitory effect on Nav1.2/SCN2A. Is lethal to mice. 1. Olamendi-Portugal, T. et al. (2017) Peptides 87, 34-40. PMID: 27871874 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (4B)



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