Anti-Human Dkk-1 Recombinant Antibody (SAA2072) (HF914023)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HF914023

abinScience

种属反应性

Human

ELISA, Neutralization

IgG1, kappa

SAA2072

Dickkopf-1, SK, hDkk-1, Dkk-1, Dickkopf-related protein 1, DKK1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O94907

Anti-Human DKK1 Antibody (SAA2072) (abinScience Cat# HF914023, RRID:AB_3729296)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Dickkopf-related protein 1 (DKK1) is a ~28 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.

1. Ahn, VE. et al. (2011) Developmental cell 21, 862-73. PMID: 22000856

2. Niehrs, C. (2006) Oncogene 25, 7469-81. PMID: 17143291

For research use only.

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

Bioactivity

Detects Human DKK1 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human DKK1 Antibody (SAA2072).

产品说明书

Anti-Human Dkk-1 Recombinant Antibody (SAA2072).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Dkk-1 Recombinant Antibody (SAA2072) (HF914023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Dkk-1 Recombinant Antibody (SAA2072) (HF914023)

概述

图片

参考文献

产品说明书

相关产品推荐

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