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InVivoMAb Anti-HAV Capsid protein VP2 Antibody (R10) (VK802010)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号VK802010
品牌abinScience
描述
InVivoMAb Anti-HAV Capsid protein VP2 Antibody (R10) [R10] (VK802010) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
种属反应性Hepatitis A virus (HAV)
应用ELISA, Neutralization
宿主Human
同种型IgG1
克隆号R10
克隆类型Monoclonal
靶标Genome polyprotein, Capsid protein VP2, P1B, Virion protein 2
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P08617
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Genome polyprotein (Capsid protein VP2) is a ~251 kDa protein. Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell.

1. Wang, X. et al. (2015) Nature 517, 85-88. PMID: 25327248
2. Wang, X. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 770-775. PMID: 28074040
3. Silberstein, E. et al. (2001) Journal of virology 75, 717-25. PMID: 11134285
4. Costafreda, MI. et al. (2018) Journal of virology 92. PMID: 29437974
5. Feigelstock, D. et al. (1998) Journal of virology 72, 6621-8. PMID: 9658108
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-HAV Capsid protein VP2 Antibody (R10)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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