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InVivoMAb Anti-Mouse SIRP alpha/CD172a Antibody (Ab25) (MX892030)

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规格：
  • 100ug
  • 1mg
数量：
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概述
货号MX892030
品牌abinScience
描述
InVivoMAb Anti-Mouse SIRPA Antibody (Ab25) [Ab25] (MX892030) is a mouse monoclonal antibody detecting Tyrosine-protein phosphatase non-receptor type substrate 1 in ELISA, Neutralization. Suitable for Mouse.
种属反应性Mouse
应用ELISA, Neutralization
同种型IgG2a, kappa
克隆号Ab25
靶标Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, mSIRP-alpha1, p84, CD172a, Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P97797
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Tyrosine-protein phosphatase non-receptor type substrate 1 (CD172a/SIRPA) is a ~56 kDa protein. Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin.

1. Nakaishi, A. et al. (2008) Journal of molecular biology 375, 650-60. PMID: 18045614
2. Sarute, N. et al. (2019) PLoS biology 17, e3000137. PMID: 30726215
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlMouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
图片

  • SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Mouse SIRPA Antibody (Ab25)

  • Bioactivity

    Detects recombinant mouse CD172a/SIRPA (Catalog No: MX892011) in indirect ELISA

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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InVivoMAb Anti-Mouse SIRP alpha/CD172a Antibody (Ab25)

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