Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12) (HV344043)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HV344043

abinScience

种属反应性

Human, Mouse

ELISA, Neutralization

IgG2a-kappa

14D12

ANGPTL4

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9BY76

Anti-Human/Mouse ANGPTL4 Antibody (14D12) (abinScience Cat# HV344043, RRID:AB_3729819)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Angiopoietin-related protein 4, Angiopoietin-like protein 4, Hepatic fibrinogen/angiopoietin-related protein, HFARP, ANGPTL4 N-terminal chain, ANGPTL4 C-terminal chain, ANGPTL4

Angiopoietin-related protein 4 (ANGPTL4) is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis.

1. Yin, W. et al. (2009) The Journal of biological chemistry 284, 13213-22. PMID: 19270337

2. Lei, X. et al. (2011) The Journal of biological chemistry 286, 15747-56. PMID: 21398697

3. Mysling, S. et al. (2016) eLife 5. PMID: 27929370

4. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144

5. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458

6. Cazes, A. et al. (2006) Circulation research 99, 1207-15. PMID: 17068295

For research use only.

Isotype Control

Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307)

SDS-PAGE

SDS-PAGE for Anti-Human/Mouse ANGPTL4 Antibody (14D12)

产品说明书

Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12) (HV344043)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12) (HV344043)

概述

图片

参考文献

产品说明书

相关产品推荐

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