货号 | HT348036 |
---|---|
品牌 | abinScience |
种属反应性 | Human |
应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
宿主 | Human |
同种型 | IgG1-kappa |
表达系统 | Mammalian Cells |
克隆类型 | Monoclonal |
靶标 | TRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2 |
内毒素水平 | Please contact the lab for this information. |
纯度 | >95% purity as determined by SDS-PAGE. |
纯化方式 | Protein A/G purified from cell culture supernatant. |
Accession号 | O14763 |
状态 | Liquid |
保存溶液 | 0.01M PBS, pH 7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
别名 | AMG655, TRAIL-R2mAb, XG1-048vw, 896731-82-1 |
背景 | Conatumumab (AMG 655) is a human monoclonal agonist antibody against human death receptor 5 (DR5, TRAILR2) (Kd: 1 nM for the long form of DR5, 0.8 nM for the short form of DR5). Conatumumab induces apoptosis via caspase activation. Conatumumab can be used in the research of cancers. . |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Detects CD262/TNFRSF10B/TRAIL-R2/DR5 in indirect ELISAs.
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