Anti-Human Fibrinogen beta chain Reference Antibody (Biciromab, RUO) (HF822016)

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概述
图片
参考文献
产品说明书

概述

货号

HF822016

品牌

abinScience

描述

Biciromab (HF822016) is a research-grade recombinant antibody targeting FGB. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Human

应用

ELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo

宿主

Mouse

同种型

IgG1-kappa

表达系统

Mammalian cells

克隆类型

Monoclonal

靶标

FGB, Fibrinogen beta chain

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P02675

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

Indium(111In)biciromab, T2G1, 138783-13-8

背景

Fibrinogen beta chain (FGB) is a ~55 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

Bioactivity

SEC-HPLC detection for Research Grade Biciromab.
SDS-PAGE

SDS-PAGE for Research Grade Biciromab
Western blot

Western blot analysis was performed using anti-FGB monoclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate

参考文献

产品说明书

Anti-Human Fibrinogen beta chain Reference Antibody (Biciromab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Fibrinogen beta chain Reference Antibody (Biciromab, RUO) (HF822016)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Fibrinogen beta chain Reference Antibody (Biciromab, RUO) (HF822016)

概述

图片

参考文献

产品说明书

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