注册
CN
首页 > 产品中心 > 抗体 > 药物对照抗体

Anti-Human MASP2 Reference Antibody (Narsoplimab, RUO) (HT020016)

价格:
规格：
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HT020016
品牌abinScience
描述
Narsoplimab (HT020016) is a research-grade recombinant antibody targeting Mannan-binding lectin serine protease 2. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG4-lambda
表达系统Mammalian cells
靶标Mannan-binding lectin serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2, MBL-associated serine protease 2, MASP2
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O00187
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名OMS721, 2108782-45-0
背景

Mannan-binding lectin serine protease 2 (MASP2) is a ~75 kDa protein. Precursor of a serum protease that activates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The lectin complement system is activated following association of lectins, such as MBL2, FCN1, FCN2 or FCN3, to carbohydrates on the pathogen surface. MASP2 is cleaved and activated by MASP1 in response to lectin-binding to pathogen carbohydrates. Can activate prothrombin to thrombin.

1. Rossi, V. et al. (2001) The Journal of biological chemistry 276, 40880-7. PMID: 11527969
2. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502
3. Degn, SE. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 3957-69. PMID: 22966085
4. Matsushita, M. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 165, 2637-42. PMID: 10946292
5. Kidmose, RT. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 15425-30. PMID: 22949645
6. Thiel, S. et al. (1997) Nature 386, 506-10. PMID: 9087411
7. Valenzuela Leon, PC. et al. (2025) Journal of medicinal chemistry 68, 4663-4671. PMID: 39924859
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)
图片

  • Bioactivity

    Detects Human MASP2 in indirect ELISAs.

  • Bioactivity

    SEC-HPLC detection for Research Grade Narsoplimab.

  • SDS-PAGE

    SDS-PAGE for Research Grade Narsoplimab.

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

Anti-Human MASP2 Reference Antibody (Narsoplimab, RUO)

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2