Anti-Human Glycogen Reference Antibody (Clervonafusp Alfa, RUO) (HY377026)

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概述

货号	HY377026
品牌	abinScience
描述	Clervonafusp Alfa (HY377026) is a research-grade recombinant antibody targeting Equilibrative nitrobenzylmercaptopurine riboside-insensit.... Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
克隆类型	Monoclonal
同种型	IgG1
表达系统	Mammalian cells
靶标	Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, 36 kDa nucleolar protein HNP36, ENT2, Equilibrative nucleoside transporter 2, SLC29A2, Hydrophobic nucleolar protein, 36 kDa, Equilibrative NBMPR-insensitive nucleoside transporter, Nucleoside transporter, ei-type, Delayed-early response protein 12, Solute carrier family 29 member 2, HNP36, DER12
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P10253
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	VAL-1221, 2145123-44-8
背景	Lysosomal alpha-glucosidase (ENT2/SLC29A2) is a ~105 kDa protein. Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. 1. Hermans, MM. et al. (2004) Human mutation 23, 47-56. PMID: 14695532 2. Pittis, MG. et al. (2008) Human mutation 29, E27-36. PMID: 18429042 3. Hermans, MM. et al. (1991) The Journal of biological chemistry 266, 13507-12. PMID: 1856189 4. Boerkoel, CF. et al. (1995) American journal of human genetics 56, 887-97. PMID: 7717400 5. Roig-Zamboni, V. et al. (2017) Nature communications 8, 1111. PMID: 29061980
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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Flow Cytometry

Flow-cytometry using anti-human SLC29A2 antibody. HepG-2 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human SLC29A2 monoclonal antibody (Catalog HY377026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using FITC anti-human SLC29A2 antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human SLC29A2 monoclonal antibody (Catalog HY377026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

参考文献

产品说明书

Anti-Human Glycogen Reference Antibody (Clervonafusp Alfa, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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Anti-Human Glycogen Reference Antibody (Clervonafusp Alfa, RUO) (HY377026)

概述

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参考文献

产品说明书

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抗体

试剂盒

实验相关试剂

Anti-Human Glycogen Reference Antibody (Clervonafusp Alfa, RUO) (HY377026)

概述

图片

参考文献

产品说明书

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