Anti-Human Alpha‑Toxin/Hla Reference Antibody (Atidortoxumab, RUO) (JN998036)

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概述

货号	JN998036
品牌	abinScience
描述	Atidortoxumab (JN998036) is a research-grade recombinant antibody targeting Alpha-hemolysin. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Staphylococcus aureus
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG1-kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Alpha-hemolysin, hly, Alpha-HL, Alpha-toxin, hla
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P09616
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	ASN-1, ASN-100(combinationofatidortoxumabandberlimatoxumab), 1939108-95-8
背景	Alpha-hemolysin (Alpha-toxin/hly) is a ~35 kDa protein. Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity. 1. Walker, B. et al. (1992) The Journal of biological chemistry 267, 10902-9. PMID: 1587866 2. Wilke, GA. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13473-8. PMID: 20624979
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Atidortoxumab

参考文献

产品说明书

Anti-Human Alpha‑Toxin/Hla Reference Antibody (Atidortoxumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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质量

浓度

体积

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g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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Anti-Human Alpha‑Toxin/Hla Reference Antibody (Atidortoxumab, RUO) (JN998036)

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重组蛋白

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实验相关试剂

Anti-Human Alpha‑Toxin/Hla Reference Antibody (Atidortoxumab, RUO) (JN998036)

概述

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产品说明书

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