Anti-Staphylococcus aureus LukGH Reference Antibody (Berlimatoxumab, RUO) (JN969016)

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概述

货号	JN969016
品牌	abinScience
描述	Berlimatoxumab (JN969016) is a research-grade recombinant antibody targeting lukG. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Staphylococcus aureus
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG1-kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	lukG
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	A0A6B5MC52
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	ASN-100(combinationofatidortoxumabandberlimatoxumab), ASN-2, 1939109-24-6
背景	Berlimatoxumab (ASN-2) is an antibody. Berlimatoxumab can be used for experiment research. • Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins., PMID:24586678 • Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity., PMID:31852826 • Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies., PMID:27467113 • Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH., PMID:25371205 • Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories., PMID:35858453 • Human antibody responses against non-covalently cell wall-bound Staphylococcus aureus proteins., PMID:29459694 • Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics., PMID:20661294 • Serum neutralizing antibody after rabies postexposure prophylaxis., PMID:945973 • Pancreatic Enzyme Replacement Therapy Use in Infants With Cystic Fibrosis Diagnosed by Newborn Screening., PMID:29176494 • Vitamin E regulates mitochondrial hydrogen peroxide generation., PMID:10490278
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Berlimatoxumab.
SDS-PAGE

SDS-PAGE for Research Grade Berlimatoxumab.

参考文献

产品说明书

Anti-Staphylococcus aureus LukGH Reference Antibody (Berlimatoxumab, RUO).pdf

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C₁ × V₁ = C₂ × V₂

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母液

C₁ (起始浓度)

V₁ (起始体积)

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V₂ (终体积)

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Anti-Staphylococcus aureus LukGH Reference Antibody (Berlimatoxumab, RUO) (JN969016)

概述

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参考文献

产品说明书

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实验相关试剂

Anti-Staphylococcus aureus LukGH Reference Antibody (Berlimatoxumab, RUO) (JN969016)

概述

图片

参考文献

产品说明书

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