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Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO) (JN072016)

价格:
规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号JN072016
品牌abinScience
描述
Pritoxaximab (JN072016) is a research-grade recombinant antibody targeting shiga toxin type 1stx1B. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Escherichia coli
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Chimeric
同种型IgG1-kappa
表达系统Mammalian cells
克隆类型Monoclonal
靶标shiga toxin type 1stx1B
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q47641
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Shigamabs(drugnameforthecombinationofpritoxaximabandsetoxaximab), caStx1, 1351470-16-0
背景

Shiga toxin subunit B (shiga toxin type 1Bstx1B) is a ~9 kDa protein. The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.

NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Bioactivity

    SEC-HPLC detection for Research Grade Pritoxaximab.

  • SDS-PAGE

    SDS-PAGE for Research Grade Pritoxaximab

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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