Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO) (JN822016)

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概述
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概述

货号	JN822016
品牌	abinScience
描述	Setoxaximab (JN822016) is a research-grade recombinant antibody targeting shiga toxin type 2stx2A. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Escherichia coli
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Chimeric
同种型	IgG1-kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	shiga toxin type 2stx2A
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P09385
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Shigamabs(drugnameforthecombinationofpritoxaximabandsetoxaximab), caStx2, 1351470-17-1
背景	Shiga-like toxin 2 subunit A (shiga toxin type 2Astx2A) is a ~35 kDa protein. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Setoxaximab.
SDS-PAGE

SDS-PAGE for Research Grade Setoxaximab

参考文献

产品说明书

Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO) (JN822016)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO) (JN822016)

概述

图片

参考文献

产品说明书

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