| 货号 | JN822016 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Escherichia coli |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Chimeric |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | shiga toxin type 2stx2A |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P09385 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | Shigamabs(drugnameforthecombinationofpritoxaximabandsetoxaximab), caStx2, 1351470-17-1 |
| 背景 | Setoxaximab is an IgG1-κ humanized chimeric antibody targeting shiga toxin type 1. • Shiga Toxin (Stx) Classification, Structure, and Function., PMID:25530917 • Shiga-toxin-converting bacteriophages., PMID:11686382 • Escherichia albertii Pathogenesis., PMID:32588811 • Shiga Toxin-Producing Escherichia coli Infections during Pregnancy., PMID:30360505 • Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice., PMID:33467588 • Targeting bacterial toxins., PMID:22441768 • Shiga toxin-induced haemolytic uraemic syndrome and the role of antibiotics: a global overview., PMID:31150744 • L-Arabinose inhibits Shiga toxin type 2-converting bacteriophage induction in Escherichia coli O157:H7., PMID:37332116 • Shiga toxin 2a and Enteroaggregative Escherichia coli--a deadly combination., PMID:26039753 • Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model., PMID:36977098 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Setoxaximab.
SDS-PAGE for Research Grade Setoxaximab
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