Anti-HCMV HCMV gH Reference Antibody (Sevirumab, RUO) (VK705016)

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概述
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概述

货号	VK705016
品牌	abinScience
描述	Sevirumab (VK705016) is a research-grade recombinant antibody targeting Envelope glycoprotein H. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG1, kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Envelope glycoprotein H, gH, gH, UL75
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P12824
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	EV27, MSL109, SDZMSL109, 138660-96-5
背景	Envelope glycoprotein H (gHUL75) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Sevirumab.
SDS-PAGE

SDS-PAGE for Research Grade Sevirumab.

参考文献

产品说明书

Anti-HCMV HCMV gH Reference Antibody (Sevirumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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Anti-HCMV HCMV gH Reference Antibody (Sevirumab, RUO) (VK705016)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-HCMV HCMV gH Reference Antibody (Sevirumab, RUO) (VK705016)

概述

图片

参考文献

产品说明书

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