Anti-HCMV HCMV gB Reference Antibody (Regavirumab, RUO) (VK665016)

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概述
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概述

货号	VK665016
品牌	abinScience
描述	Regavirumab (VK665016) is a research-grade recombinant antibody targeting Envelope glycoprotein B. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG1, kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Envelope glycoprotein B, gB, UL55
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P06473
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	C23, MCAC23, TI-23, 153101-26-9
背景	Envelope glycoprotein B (gB) is a ~102 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Regavirumab.
SDS-PAGE

SDS-PAGE for Research Grade Regavirumab.

参考文献

产品说明书

Anti-HCMV HCMV gB Reference Antibody (Regavirumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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Anti-HCMV HCMV gB Reference Antibody (Regavirumab, RUO) (VK665016)

概述

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参考文献

产品说明书

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实验相关试剂

Anti-HCMV HCMV gB Reference Antibody (Regavirumab, RUO) (VK665016)

概述

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参考文献

产品说明书

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