





| 货号 | VK539036 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Libivirumab (VK539036) is a research-grade recombinant antibody targeting Large envelope protein. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 种属反应性 | Hepatitis B virus (HBV) |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 表达系统 | Mammalian cells |
| 克隆类型 | Monoclonal |
| 靶标 | Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P03142 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | 17.1.41, HepeX-B(combinationofexbivirumabandlibivirumab), 569658-79-3 |
| 背景 | Large envelope protein (HBsAg) is a ~42 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Libivirumab.

Detects S/L-HBsAg/L glycoprotein in indirect ELISAs.

SDS-PAGE for Research Grade Libivirumab







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