Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Gedivumab, RUO) (VK515046)

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概述
图片
参考文献
产品说明书

概述

货号

VK515046

品牌

abinScience

描述

Gedivumab (VK515046) is a research-grade recombinant antibody targeting HA/Hemagglutinin. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Influenza A virus (H1, H2, H3, H5, H7 subtype)

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

宿主

Human

同种型

IgG1, kappa

表达系统

Mammalian cells

克隆类型

Monoclonal

靶标

HA/Hemagglutinin

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

C6KNH7

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

MHAA4549A, RO6876802, RG7745, 1807954-17-1

背景

Hemagglutinin (HA) is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

Bioactivity

SEC-HPLC detection for Research Grade Gedivumab.
SDS-PAGE

SDS-PAGE for Research Grade Gedivumab.

参考文献

产品说明书

Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Gedivumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Gedivumab, RUO) (VK515046)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Gedivumab, RUO) (VK515046)

概述

图片

参考文献

产品说明书

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