





| 货号 | VK632026 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Rafivirumab (VK632026) is a research-grade recombinant antibody targeting G/Glycoprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 种属反应性 | Rabies virus (RABV) |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG1, lambda |
| 表达系统 | Mammalian cells |
| 克隆类型 | Monoclonal |
| 靶标 | G/Glycoprotein |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | O92284 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | CR57, NM57, S057, CR57, SO57, Ormutivimab, 944548-37-2 |
| 背景 | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Rafivirumab.

Detects Human G/Glycoprotein in indirect ELISAs.

SDS-PAGE for Research Grade Rafivirumab







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