| 货号 | HW328296 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | Fusion-[GCG (glucagon) 98-127 (glucagon-like peptide 1, GLP1) 7-36]2-IgG4-Fc (Fragment constant) |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P43220 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | 923950-08-7 |
| 背景 | Liraglutide, 97% similar to native human GLP-1, differs primarily by substituting arginine for lysine at position 34 and involves attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer at the remaining lysine residue at position 26. • The physiology of glucagon-like peptide 1., PMID:17928588 • Glucagon-like peptide-1 receptor: mechanisms and advances in therapy., PMID:39289339 • The structure and function of the glucagon-like peptide-1 receptor and its ligands., PMID:21950636 • Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist., PMID:33177239 • Glucagon-like peptide-1 receptor., PMID:39626623 • Prognostic impact of glucagon-like peptide-1 receptor (GLP1R) expression on cancer survival and its implications for GLP-1R agonist therapy: an integrative analysis across multiple tumor types., PMID:39777709 • Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials., PMID:28244632 • Glucagon-like-peptide 1 receptor agonism and attempted suicide: A Mendelian randomisation study to assess a potential causal association., PMID:38778795 • Glucagon-Like Peptide-1 Receptor Agonism and Suicide Risk: Evidence From Mendelian Randomization., PMID:38879463 • GLP-1, GIP/GLP-1, and GCGR/GLP-1 receptor agonists: Novel therapeutic agents for metabolic dysfunction-associated steatohepatitis., PMID:39735270 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Dulaglutide.
Detects GLP1R in indirect ELISAs.
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