| 货号 | HY112016 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Chimeric |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | INSR, IR, CD220, Insulin receptor |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P06213 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | AGT-181, HIRMAb-IDUA, 1815583-32-4 |
| 背景 | Ersodetug is an anti-INSR (insulin receptor) human IgG2 κ monoclonal antibody. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002). • Transcriptional Regulation of INSR, the Insulin Receptor Gene., PMID:31795422 • Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer., PMID:24338270 • The neuronal insulin receptor in its environment., PMID:27889917 • Insulin receptor orchestrates kidney antibacterial defenses., PMID:38976738 • Activation of the insulin receptor by insulin-like growth factor 2., PMID:38521788 • Alternative splicing of human insulin receptor gene (INSR) in type I and type II skeletal muscle fibers of patients with myotonic dystrophy type 1 and type 2., PMID:23666741 • Analyzing structural differences between insulin receptor (IR) and IGF1R for designing small molecule allosteric inhibitors of IGF1R as novel anti-cancer agents., PMID:32877816 • Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation., PMID:34644569 • Insulin Analogues with Altered Insulin Receptor Isoform Binding Specificities and Enhanced Aggregation Stabilities., PMID:34591477 • Deciphering Brain Insulin Receptor and Insulin-Like Growth Factor 1 Receptor Signalling., PMID:27631195 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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