Anti-Human F7 Reference Antibody (12D10-Fab, RUO) (HY060013)

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概述
图片
参考文献
产品说明书

概述

货号

HY060013

品牌

abinScience

描述

Anti-Human F7 (12D10-Fab) (HY060013) is a research-grade recombinant antibody targeting F7. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Human

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

宿主

Chimeric

同种型

Fab-nd-nd

克隆号

12D10-Fab

表达系统

Mammalian cells

克隆类型

Monoclonal

靶标

F7, Proconvertin, SPCA, Serum prothrombin conversion accelerator, Coagulation factor VII, Eptacog alfa

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P08709

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Coagulation factor VII (F7) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

参考文献

产品说明书

Anti-Human F7 Reference Antibody (12D10-Fab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human F7 Reference Antibody (12D10-Fab, RUO) (HY060013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human F7 Reference Antibody (12D10-Fab, RUO) (HY060013)

概述

图片

参考文献

产品说明书

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