货号 | YP115016 |
---|---|
品牌 | abinScience |
种属反应性 | General |
应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
宿主 | Chimeric |
同种型 | IgG1-kappa |
表达系统 | Mammalian Cells |
克隆类型 | Monoclonal |
靶标 | Ganglioside GD2 |
内毒素水平 | Please contact the lab for this information. |
纯度 | >95% purity as determined by SDS-PAGE. |
纯化方式 | Protein A/G purified from cell culture supernatant. |
Accession号 | 65988-71-8 |
状态 | Liquid |
保存溶液 | 0.01M PBS, pH 7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
别名 | 14.18, MAb-14.18, MOABCh14.18, 1363687-32-4, DGK07804 |
背景 | Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab potently enlongs event-free survival and overall survival, in high-risk neuroblastoma treatment, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (interleukin-2 [IL-2]), and isotretinoin (13-cis-retinoic acid [RA]). |
Note | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Dinutuximab.
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