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Research Grade Evinacumab (HV176016)

价格:
规格:
  • 100ug
  • 1mg
数量:
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概述
货号HV176016
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG4-kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标ANG-5, Angiopoietin-like protein 3, ANGPT5, Angiopoietin-5, ANGPTL3, Angiopoietin-related protein 3
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9Y5C1
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名REGN1500, 1446419-85-7
背景Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia.
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Evinacumab.

  • Bioactivity

    Detects Human ANGPTL3 in direct ELISAs.

  • SDS-PAGE

    SDS-PAGE for Research Grade Evinacumab

参考文献

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