



| 货号 | HT009016 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Nadecnemab (HT009016) is a research-grade recombinant antibody targeting GFR-alpha-3. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 同种型 | IgG4-Kappa |
| 表达系统 | Mammalian cells |
| 靶标 | GFR-alpha-3, GDNF receptor alpha-3, GDNF family receptor alpha-3, GDNFR-alpha-3, GFRA3 |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | O60609 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | REGN5069, 2377679-19-9 |
| 背景 | GDNF family receptor alpha-3 (GFRA3) is a ~44 kDa protein. Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons. ARTN-binding leads to autophosphorylation and activation of the RET receptor. 1. Li, J. et al. (2019) eLife 8. PMID: 31535977 2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107) |

SEC-HPLC detection for Research Grade Nadecnemab.

Detects GFRA3 in indirect ELISAs.





24小时产品查询

扫一扫关注我们

专属渠道经理