首页 > 产品中心 > 抗体 > 药物对照抗体

Anti-Human OSMR beta Reference Antibody (Vixarelimab, RUO) (HV716016)

价格:
规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HV716016
品牌abinScience
描述
Vixarelimab (HV716016) is a research-grade recombinant antibody targeting OSMRB. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG4-IgG1, Lambda
表达系统Mammalian cells
靶标OSMRB, IL-31R subunit beta, Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31RB, IL-31R-beta, OSMR, IL-31 receptor subunit beta
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q99650
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名KPL-716, 30C6(N73D), BIIB069, BIIB-069, 2243320-83-2
背景

Oncostatin-M-specific receptor subunit beta (OSMR/IL-31RB) is a ~110 kDa protein. Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.

NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)
图片
  • Bioactivity

    SEC-HPLC detection for Research Grade Vixarelimab.

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐