| 货号 | HY110026 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Chimeric |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | SAA, Serum amyloid A-1 protein, SAA1, Amyloid fibril protein AA |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P0DJI8 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | 11-1F4, CAEL101, CAEL-101, NSC-711516, 2414866-63-8 |
| 背景 | Anselamimab (CAEL-101) a humanized IgG1-κ anti-Amyloid fibrils antibody targeting to serum amyloid A1 (SAA1). • Overexpression of serum amyloid a 1 induces depressive-like behavior in mice., PMID:27608955 • Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2., PMID:23223242 • Serum amyloid A levels are associated with polymorphic variants in the serum amyloid A 1 and 2 genes., PMID:30852808 • Large-scale isotype-specific quantification of Serum amyloid A 1/2 by multiple reaction monitoring in crude sera., PMID:22300576 • Increased susceptibility of serum amyloid A 1.1 to degradation by MMP-1: potential explanation for higher risk of type AA amyloidosis., PMID:18815155 • Diversity and complexity of the mouse Saa1 and Saa2 genes., PMID:24521869 • The role of PPAR activation during the systemic response to brain injury., PMID:25994490 • Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A., PMID:20890286 • Hematological and acute-phase responses to diet-induced obesity in IL-6 KO mice., PMID:21996012 • Clustering of six human 11p15 gene homologs within a 500-kb interval of proximal mouse chromosome 7., PMID:7698755 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Anselamimab.
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