| 货号 | VK632036 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Rabies virus (RABV) |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Humanized |
| 同种型 | IgG1, kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | G, Glycoprotein |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | O92284, P08667 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | CTB012, CTB-012, CTB012, SYN023, CAS: 2419087-89-9 |
| 背景 | Mazorelvimab (SYN023) is a combination of CTB011 and CTB012 humanized monoclonal antibodies cocktail against rabies virus (RABV). Mezagitamab binds to non-overlapping epitopes on RABV glycoprotein (G). Mezagitamab has potential application in the prevention of rabies. • The glycoprotein G of rhabdoviruses., PMID:7605197 • Chandipura viral glycoprotein (CNV-G) promotes Gectosome generation and enables delivery of intracellular therapeutics., PMID:38702887 • The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism., PMID:32937107 • Viral membrane fusion: is glycoprotein G of rhabdoviruses a representative of a new class of viral fusion proteins?, PMID:15933774 • G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates., PMID:21693135 • Structure and Dynamics of Immunoglobulin G Glycoproteins., PMID:30484251 • Chemical-Synthesis-Based Approach to Glycoprotein Functions in the Endoplasmic Reticulum., PMID:33107166 • Human metapneumovirus glycoprotein G disrupts mitochondrial signaling in airway epithelial cells., PMID:23626834 • Boronic acid functionalized g-C3N4 nanosheets for ultrasensitive and selective sensing of glycoprotein in the physiological environment., PMID:29480294 • 4'-(8-(4-Methylimidazole)-octyloxy)-arctigenin: The first inhibitor of fish rhabdovirus glycoprotein., PMID:37385462 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Mazorelvimab
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