首页 > 产品中心 > 抗体 > 药物对照抗体

Research Grade Mazorelvimab (VK632036)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述
  • 图片
  • 参考文献
  • 产品说明书
概述
货号VK632036
品牌abinScience
种属反应性Rabies virus (RABV)
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Humanized
同种型IgG1, kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标G, Glycoprotein
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O92284, P08667
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名CTB012, CTB-012, CTB012, SYN023, CAS: 2419087-89-9
背景Mazorelvimab (SYN023) is a combination of CTB011 and CTB012 humanized monoclonal antibodies cocktail against rabies virus (RABV). Mezagitamab binds to non-overlapping epitopes on RABV glycoprotein (G). Mezagitamab has potential application in the prevention of rabies.
• The glycoprotein G of rhabdoviruses., PMID:7605197
• Chandipura viral glycoprotein (CNV-G) promotes Gectosome generation and enables delivery of intracellular therapeutics., PMID:38702887
• The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism., PMID:32937107
• Viral membrane fusion: is glycoprotein G of rhabdoviruses a representative of a new class of viral fusion proteins?, PMID:15933774
• G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates., PMID:21693135
• Structure and Dynamics of Immunoglobulin G Glycoproteins., PMID:30484251
• Chemical-Synthesis-Based Approach to Glycoprotein Functions in the Endoplasmic Reticulum., PMID:33107166
• Human metapneumovirus glycoprotein G disrupts mitochondrial signaling in airway epithelial cells., PMID:23626834
• Boronic acid functionalized g-C3N4 nanosheets for ultrasensitive and selective sensing of glycoprotein in the physiological environment., PMID:29480294
• 4'-(8-(4-Methylimidazole)-octyloxy)-arctigenin: The first inhibitor of fish rhabdovirus glycoprotein., PMID:37385462
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
参考文献

相关产品推荐