| 货号 | HY550026 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Humanized |
| 同种型 | IgG4-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | Vimentin, VIM |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P08670 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | hzVSF-v13, hzVSF_var13, HzVSF-13, 2460809-80-5 |
| 背景 | Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab can be used in severe COVID-19 studies. • Roles of vimentin in health and disease., PMID:35487686 • Spatial single-cell protein landscape reveals vimentinhigh macrophages as immune-suppressive in the microenvironment of hepatocellular carcinoma., PMID:39327501 • Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin., PMID:37641404 • FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression., PMID:37915048 • Vimentin Inhibits Dengue Virus Type 2 Invasion of the Blood-Brain Barrier., PMID:35433510 • Vimentin on the move: new developments in cell migration., PMID:30505430 • Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma., PMID:38901494 • Vimentin as a universal receptor for pseudorabies virus infection in pig and human cells., PMID:39549807 • PROTAC-mediated vimentin degradation promotes terminal erythroid differentiation of pluripotent stem cells., PMID:39294765 • Vimentin, colon cancer progression and resistance to butyrate and other HDACis., PMID:27072512 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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