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Research Grade Ozuriftamab (HX930016)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述
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  • 参考文献
  • 产品说明书
概述
货号HX930016
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Humanized
同种型IgG1-kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标ROR2, Neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q01974
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名BA302, 2460399-44-2
背景Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC.
• A proteogenomic portrait of lung squamous cell carcinoma., PMID:34358469
• WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth., PMID:36622276
• ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma., PMID:38975886
• Robinow syndrome., PMID:12011143
• Ror2 as a therapeutic target in cancer., PMID:25614331
• Prognostic value of receptor tyrosine kinase-like orphan receptor (ROR) family in cancer: A meta-analysis., PMID:31174180
• Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis., PMID:32951408
• The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis., PMID:23233346
• Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer., PMID:36463543
• Purification and characterization of the extracellular region of human receptor tyrosine kinase like orphan receptor 2 (ROR2)., PMID:30826310
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Bioactivity

    Detects Human ROR2/NTRKR2 in indirect ELISAs.

参考文献

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