Anti-Human DAG1/Dystroglycan Reference Antibody (DAG-6F4, RUO) (HC564016)

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概述

货号	HC564016
品牌	abinScience
描述	Anti-Human DAG1/Dystroglycan (DAG-6F4) (HC564016) is a research-grade recombinant antibody targeting Dystrophin-associated glycoprotein 1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
克隆类型	Monoclonal
同种型	IgG
克隆号	DAG-6F4
表达系统	Mammalian cells
靶标	Dystrophin-associated glycoprotein 1, DAG1, Alpha-DG, Dystroglycan, Beta-DG
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q14118
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	DAG-6F4, DAG6F4, DAG6F4
背景	Dystroglycan 1 (DAG1) is a ~97 kDa protein. The dystroglycan complex is involved in a number of signaling events and processes including laminin deposition and extracellular matrix assembly, acetylcholine receptor clustering, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, epithelial polarization, and epithelium branching morphogenesis. Required for the formation of photoreceptor ribbon synapses, and long-term maintenance of inhibitory synapses in cerebellar Purkinje cells. Also involved in the positive regulation of cartilage formation through agrin (AGRN) binding and up-regulation of SOX9, a transcription factor that plays a key role in chondrocytes differentiation. 1. Eldridge, S. et al. (2016) Annals of the rheumatic diseases 75, 1228-35. PMID: 26290588
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human DAG1/Dystroglycan (DAG-6F4)

参考文献

产品说明书

Anti-Human DAG1/Dystroglycan Reference Antibody (DAG-6F4, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

Anti-Human DAG1/Dystroglycan Reference Antibody (DAG-6F4, RUO) (HC564016)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DAG1/Dystroglycan Reference Antibody (DAG-6F4, RUO) (HC564016)

概述

图片

参考文献

产品说明书

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