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Research Grade Batiraxcept (HC347036)

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概述
货号HC347036
品牌abinScience
描述
Batiraxcept (HC347036) is a research-grade recombinant antibody targeting AXLLG. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Functional assay, Research in vivo
同种型Fusion - [AXL (AXL receptor tyrosine kinase, ARK, JTK11, Tyro7, UFO)]2 - IGHG1 Fc (Fragment constant)
表达系统Mammalian cells
靶标AXLLG, Growth arrest-specific protein 6, AXL receptor tyrosine kinase ligand, GAS6, GAS-6
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q14393
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名AVB-500, AVB-S6-500, Aravive-S6, MYD1Fc, Ruga-S6, 2268717-61-7
背景

Growth arrest-specific protein 6 (GAS6) is a ~74 kDa protein. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

NoteFor research use only. Not suitable for clinical or therapeutic use.
图片

  • SDS-PAGE

    SDS-PAGE for Research Grade Batiraxcept

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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