Anti-Human Cripto-1 Reference Antibody (BIIB015, RUO) (HY096016)

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概述

货号	HY096016
品牌	abinScience
描述	Anti-Human TDGF1/CRIPTO (BIIB015) (HY096016) is a research-grade recombinant antibody targeting Cripto-1 growth factor. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
克隆类型	Monoclonal
同种型	IgG
克隆号	BIIB015
表达系统	Mammalian cells
靶标	Cripto-1 growth factor, Teratocarcinoma-derived growth factor 1, TDGF1, CRIPTO, Epidermal growth factor-like cripto protein CR1, CRGF
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P13385
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	BIIB015
背景	Protein Cripto (TDGF1) is a ~21 kDa protein. GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. 1. Lee, GH. et al. (2016) The Journal of cell biology 215, 705-718. PMID: 27881714 2. Bianco, C. et al. (2002) Molecular and cellular biology 22, 2586-97. PMID: 11909953
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human TDGF1/CRIPTO (BIIB015)

参考文献

产品说明书

Anti-Human Cripto-1 Reference Antibody (BIIB015, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Cripto-1 Reference Antibody (BIIB015, RUO) (HY096016)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Cripto-1 Reference Antibody (BIIB015, RUO) (HY096016)

概述

图片

参考文献

产品说明书

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