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Research Grade hEPO-Fc (HB152016)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
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  • 参考文献

  • 产品说明书

概述
货号HB152016
品牌abinScience
描述
Anti-Human EPOR (rhEPO-Fc) (HB152016) is a research-grade recombinant antibody targeting EPOR. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用Functional assay
表达系统Mammalian cells
种属Homo sapiens (Human)
靶标EPOR, Erythropoietin receptor, EPO-R
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P01588
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

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1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848
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2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695
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3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696
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4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939
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5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108
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6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159
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NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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