首页 > 产品中心 > 抗体 > 药物对照抗体

Anti-Human FGF basic/FGF2/bFGF Reference Antibody (HuGAL-F2, RUO) (HY398016)

价格:
规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HY398016
品牌abinScience
描述
Anti-Human FGF2/bFGF (HuGAL-F2) (HY398016) is a research-grade recombinant antibody targeting bFGF. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG
克隆号HuGAL-F2
表达系统Mammalian cells
克隆类型Monoclonal
靶标bFGF, FGF2, Basic fibroblast growth factor, HBGF-2, FGFB, FGF-2, Heparin-binding growth factor 2, Fibroblast growth factor 2
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P09038
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名HuGAL-F2, HuGALF2, HuGALF2
背景

Fibroblast growth factor 2 (FGF2/bFGF) is a ~30 kDa protein. Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro.

1. Ornitz, DM. et al. (1996) The Journal of biological chemistry 271, 15292-7. PMID: 8663044
2. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677
3. Shimoyama, Y. et al. (1991) Japanese journal of cancer research : Gann 82, 1263-70. PMID: 1721615
4. Gautschi, P. et al. (1986) FEBS letters 204, 203-7. PMID: 3732516
5. Gimenez-Gallego, G. et al. (1986) Biochemical and biophysical research communications 135, 541-8. PMID: 3964259
6. Mori, S. et al. (2013) PloS one 8, e57927. PMID: 23469107
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human FGF2/bFGF (HuGAL-F2)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐