Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO) (CS870016)

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概述
图片
参考文献
产品说明书

概述

货号

CS870016

品牌

abinScience

描述

Gilvetmab (CS870016) is a research-grade recombinant antibody targeting CD279. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Canine

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

宿主

Canine

同种型

IgG2-kappa

表达系统

Mammalian cells

克隆类型

Monoclonal

经测试应用

靶标

CD279/PDCD1/PD1

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

E2RPS2

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

AH-PD1, 1808081-43-7

背景

Gilvetmab is a potent caninized anti-PD-1 monoclonal antibody. gilvetmab blocks the interaction between PD-1 and its ligand PDL-1.
• Diagnostic value of soluble programmed cell death protein-1 in type-1 autoimmune hepatitis in Egyptian children., PMID:31762332

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

Bioactivity

Detects Dog CD279 in indirect ELISAs.
SEC-HPLC

SEC-HPLC detection for Research Grade Gilvetmab.
SDS-PAGE

SDS-PAGE for Research Grade Gilvetmab
Western blot

Western blot analysis was performed using anti-dog PD1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Dog CD279/PDCD1/PD1 (Catalog No: CS870011)
Lane 2: negative control

参考文献

产品说明书

Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO) (CS870016)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO) (CS870016)

概述

图片

参考文献

产品说明书

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