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Research Grade Forimtamig (HP458026)

价格:
规格:
  • 100ug
  • 1mg
数量:
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概述
货号HP458026
品牌abinScience
种属反应性Human
应用Research Grade Biosimilar
宿主Human
同种型IgG1-lambda/kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标GPRC5D, G-protein coupled receptor family C group 5 member D, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G, purified from cell culture supernatant.
Accession号Q9NZD1 & P07766
状态Liquid
保存溶液0.01M PBS,pH7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名rg6234,CAS:2649379-96-2
背景Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
NoteFor research use only. Not for use in clinical or therapeutic applications.
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