Anti-Canine IL-31 Reference Antibody (Riltovetbart, RUO) (CV678036)

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概述
图片
参考文献
产品说明书

概述

货号

CV678036

品牌

abinScience

描述

Riltovetbart (CV678036) is a research-grade recombinant antibody targeting IL-31. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Canine

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

宿主

Canine

同种型

IgG2-kappa

表达系统

Mammalian cells

克隆类型

Monoclonal

靶标

IL-31, Interleukin-31, IL31

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

C7G0W1

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

2641479-65-2

背景

Tirnovetmab (KIND-016) is an antibody. Tirnovetmab can be used for experiment research.
• The IL-4, IL-13 and IL-31 pathways in atopic dermatitis., PMID:34106037
• IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis., PMID:37831760
• Interleukin-31: The "itchy" cytokine in inflammation and therapy., PMID:33629401
• A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1., PMID:24373353
• Seladelpar treatment reduces IL-31 and pruritus in patients with primary biliary cholangitis., PMID:38117036
• Nemolizumab: First Approval., PMID:35834124
• Nemolizumab: An Innovative Biologic Treatment to Control Interleukin 31, a Key Mediator in Atopic Dermatitis and Prurigo Nodularis., PMID:35842249
• The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching., PMID:32673566
• Pruritus as a Distinctive Feature of Type 2 Inflammation., PMID:33807098
• Targeting Interleukin-31 in Prurigo., PMID:37888922

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

SDS-PAGE

SDS-PAGE for Research Grade Riltovetbart

参考文献

产品说明书

Anti-Canine IL-31 Reference Antibody (Riltovetbart, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Canine IL-31 Reference Antibody (Riltovetbart, RUO) (CV678036)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Canine IL-31 Reference Antibody (Riltovetbart, RUO) (CV678036)

概述

图片

参考文献

产品说明书

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