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Anti-Human aPC/Activated protein C Reference Antibody (TPP-4885/BAY1896502, RUO) (HY476026)

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概述
货号HY476026
品牌abinScience
描述
Anti-Human APC/Activated protein C (TPP-4885/BAY1896502) (HY476026) is a research-grade recombinant antibody targeting Anticoagulant protein C. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG2
克隆号TPP-4885/BAY1896502
靶标Anticoagulant protein C, Vitamin K-dependent protein C, Blood coagulation factor XIV, Autoprothrombin IIA
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P04070
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名TPP-2312, BAY1316786
背景

Vitamin K-dependent protein C (APC/Activated protein C) is a ~52 kDa protein. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function.

1. Kovács, KB. et al. (2015) Thrombosis research 135, 718-26. PMID: 25618265
2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037
3. Ding, Q. et al. (2015) Blood 125, 2428-34. PMID: 25651845
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
图片

  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human APC/Activated protein C (TPP-4885/BAY1896502)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human aPC/Activated protein C Reference Antibody (TPP-4885/BAY1896502, RUO)

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