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Anti-HCV Envelope glycoprotein E2 Reference Antibody (HuMax-HepC, RUO) (VK681026)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
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  • 概述

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  • 参考文献

  • 产品说明书

概述
货号VK681026
品牌abinScience
描述
Anti-HCV NS1/Envelope glycoprotein E2 (HuMax-HepC) (VK681026) is a research-grade recombinant antibody targeting NS1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Hepatitis C Virus (HCV)
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG
克隆号HuMax-HepC
表达系统Mammalian cells
克隆类型Monoclonal
靶标NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P27958
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名HuMax-HepC, HuMaxHepC
背景

Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802
2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612
3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025
4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511
5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-HCV NS1/Envelope glycoprotein E2 (HuMax-HepC)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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