Anti-Human HJV/Hemojuvelin Reference Antibody (DISC-0974, RUO) (HV013016)

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概述
图片
参考文献
产品说明书

概述

货号

HV013016

品牌

abinScience

描述

Anti-Human HJV/Hemojuvelin (DISC-0974) (HV013016) is a research-grade recombinant antibody targeting Hemojuvelin BMP coreceptor. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Human

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

同种型

IgG

克隆号

DISC-0974

表达系统

Mammalian cells

靶标

Hemojuvelin BMP coreceptor, HJV, RGMC, RGM domain family member C, Hemochromatosis type 2 protein, Hemojuvelin, HFE2

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

Q6ZVN8

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

DISC-0974, DISC0974, DISC0974

背景

Hemojuvelin (HJV) is a ~45 kDa protein. Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.

1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

图片

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human HJV/Hemojuvelin (DISC-0974)
Flow cytometry

Flow-cytometry using anti-human HJV antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human HJV monoclonal antibody (Catalog HV013016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献

产品说明书

Anti-Human HJV/Hemojuvelin Reference Antibody (DISC-0974, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HJV/Hemojuvelin Reference Antibody (DISC-0974, RUO) (HV013016)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HJV/Hemojuvelin Reference Antibody (DISC-0974, RUO) (HV013016)

概述

图片

参考文献

产品说明书

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