Anti-Human ErbB2/Her2 & CD3 epsilon Reference Antibody (AMX-818, RUO) (HY286246)

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概述

货号	HY286246
品牌	abinScience
描述	Anti-Human CD340/ERBB2/HER2/NEU&CD3 Antibody (AMX-818) (HY286246) is a research-grade recombinant antibody targeting CD340. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
宿主	Human
克隆类型	Monoclonal
同种型	tandem scFv
克隆号	AMX-818
靶标	CD340, EC:2.7.10.1, ERBB2, HER2, MLN 19, MLN19, Metastatic lymph node gene 19 protein, NEU, NGL, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, 4-1BB ligand, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
内毒素水平	< 10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P04626 & P07766
状态	Liquid
保存溶液	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	AMX-818, AMX818, AMX818
背景	Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2 & CD3) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD340/ERBB2/HER2/NEU (AMX-818)

参考文献

产品说明书

Anti-Human ErbB2/Her2 & CD3 epsilon Reference Antibody (AMX-818, RUO).pdf

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母液

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Anti-Human ErbB2/Her2 & CD3 epsilon Reference Antibody (AMX-818, RUO) (HY286246)

概述

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参考文献

产品说明书

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重组蛋白

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Anti-Human ErbB2/Her2 & CD3 epsilon Reference Antibody (AMX-818, RUO) (HY286246)

概述

图片

参考文献

产品说明书

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