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Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO) (HB912016)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
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  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HB912016
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG1-kappa
克隆号Mik beta 1
表达系统Mammalian cells
靶标IL-2R subunit beta, Interleukin-15 receptor subunit beta, IL2RB, IL-2 receptor subunit beta, CD122, High affinity IL-2 receptor subunit beta, p75, Interleukin-2 receptor subunit beta, IL-2RB, p70-75, IL15RB
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P14784
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Mik-beta-1, Mikbeta1, Mik-beta1
背景

Interleukin-2 receptor subunit beta (CD122/IL2RB) is a ~61 kDa protein. Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.

1. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770
2. Zhang, Z. et al. (2019) The Journal of experimental medicine 216, 1311-1327. PMID: 31040185
文献1. J Hakimi, et al. Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC. J Immunol. 1993 Jul 15;151(2):1075-85. [HB912016]
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CD122/IL2RB (Mik beta 1).

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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