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Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO) (HP960016)

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规格:
  • 100ug
  • 1mg
  • 5mg
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  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HP960016
品牌abinScience
描述
Anti-Human CLEC2D/OCIL/LLT1 (ZM008) (HP960016) is a research-grade recombinant antibody targeting CLAX. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG
克隆号ZM008
表达系统Mammalian cells
靶标CLAX, C-type lectin domain family 2 member D, Osteoclast inhibitory lectin, CLEC2D, Lectin-like transcript 1, Lectin-like NK cell receptor, OCIL, LLT-1, LLT1
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9UHP7
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名ZM008
背景

C-type lectin domain family 2 member D (CLEC2D/OCIL) is a ~21 kDa protein. Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.

1. Rosen, DB. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7796-9. PMID: 16339513
2. Germain, C. et al. (2010) The Journal of biological chemistry 285, 36207-15. PMID: 20843815
3. Hu, YS. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 89-99. PMID: 14753741
4. Gange, CT. et al. (2004) The Journal of biological chemistry 279, 29043-9. PMID: 15123656
5. Mathew, PA. et al. (2004) Molecular immunology 40, 1157-63. PMID: 15104121
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CLEC2D/OCIL/LLT1 (ZM008)

  • Bioactivity

    Detects recombinant human CLEC2D/OCIL/LLT1 (Catalog No: HP960012) in indirect ELISA

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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