Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO) (HV585016)

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概述

货号	HV585016
品牌	abinScience
描述	Anti-Human CD352/SLAMF6 (SGN-CD352A) (HV585016) is a research-grade recombinant antibody targeting CD352. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG
克隆号	SGN-CD352A
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	CD352, NTB-A, NK-T-B-antigen, KALI, SLAMF6, Activating NK receptor, SLAM family member 6
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q96DU3
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	SGN-CD352A, SGNCD352A, SGNCD352A
背景	SLAM family member 6 (CD352/SLAMF6) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. Positive signaling in NK cells implicates phosphorylation of VAV1. 1. Bottino, C. et al. (2001) The Journal of experimental medicine 194, 235-46. PMID: 11489943 2. Eissmann, P. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 3170-7. PMID: 16920955 3. Chatterjee, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 1206-12. PMID: 22184727 4. Chatterjee, M. et al. (2012) The Journal of biological chemistry 287, 38168-77. PMID: 22989874
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD352/SLAMF6 (SGN-CD352A)

参考文献

产品说明书

Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO) (HV585016)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO) (HV585016)

概述

图片

参考文献

产品说明书

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