Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (CNTO 860, RUO) (HB058036)

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货号	HB058036
品牌	abinScience
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG
克隆号	CNTO 860
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P13726
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	CNTO-860, CNTO860, CNTO860
背景	Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).
文献	1. Richard S. Tawadros, et al., CNTO 860, a humanized anti-tissue factor monoclonal antibody, significantly improves tumor response to paclitaxel in a xenograft model of colon cancer. EXPERIMENTAL AND MOLECULAR THERAPEUTICS 20: ADVANCES IN CANCER THERAPEUTICS 2006. [HB058036]
Note	For research use only. Not suitable for clinical or therapeutic use.

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD142/F3/TF (CNTO 860)

产品说明书

Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (CNTO 860, RUO).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (CNTO 860, RUO) (HB058036)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (CNTO 860, RUO) (HB058036)

概述

图片

参考文献

产品说明书

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